| 1 | 21:33.75 | Maegan KrifchinTownwide Fund of Huntington Thanksgiving Day Run | Townwide Fund of Huntington Thanksgiving Day Run | 2021 |
| 2 | 22:04.11 | Laurel FisherEJ Autism 4 Mile Run/Walk | EJ Autism 4 Mile Run/Walk | 2026 |
| 3 | 22:58.80 | Elizabeth CaldwellIndependence Day 4 Mile Run/Walk | Independence Day 4 Mile Run/Walk | 2023 |
| 4 | 23:00.38 | Alyssa SaleseTownwide Fund of Huntington Thanksgiving 4 Mile | Townwide Fund of Huntington Thanksgiving 4 Mile | 2022 |
| 5 | 23:07.3 | Victoria Kornieva-RobitailleSnowflake 4 Mile | Snowflake 4 Mile | 2020 |
| 6 | 23:19.66 | Bonnie AverbuchTownwide Fund of Huntington Thanksgiving Day 4 Mile | Townwide Fund of Huntington Thanksgiving Day 4 Mile | 2019 |
| 7 | 23:23.29 | Heather WilliamsThe 11th Annual Jigsaw 4 mile Run/Walk | The 11th Annual Jigsaw 4 mile Run/Walk | 2017 |
| 8 | 23:24.97 | Jade RobertsonTownwide Fund of Huntington Thanksgiving 4 Mile | Townwide Fund of Huntington Thanksgiving 4 Mile | 2023 |
| 9 | 23:34 | Leonora PetrinaThe 10th Annual Jigsaw 4 mile Run/Walk | The 10th Annual Jigsaw 4 mile Run/Walk | 2016 |
| 10 | 23:38.43 | Katie McGrathThe 11th Annual Jigsaw 4 mile Run/Walk | The 11th Annual Jigsaw 4 mile Run/Walk | 2017 |
| 11 | 23:43.21 | Lara DorskyIndependence Day 4 Mile Run/Walk | Independence Day 4 Mile Run/Walk | 2022 |
| 12 | 23:47.46 | Lena EdelsteinJigsaw 4 Mile Run | Jigsaw 4 Mile Run | 2019 |
| 13 | 24:08.91 | Grace WeigeleTownwide Fund of Huntington Thanksgiving Day 4 Mile | Townwide Fund of Huntington Thanksgiving Day 4 Mile | 2019 |
| 14 | 24:10.46 | Colleen BuckleyTownwide Fund of Huntington Thanksgiving 4 Mile | Townwide Fund of Huntington Thanksgiving 4 Mile | 2023 |
| 15 | 24:15.89 | Elizabeth LaMarcaEJ Autism 4 Mile Run/Walk | EJ Autism 4 Mile Run/Walk | 2026 |
| 16 | 24:17.36 | Shari KlarfeldThe 11th Annual Jigsaw 4 mile Run/Walk | The 11th Annual Jigsaw 4 mile Run/Walk | 2017 |
| 17 | 24:19.98 | Emily WickardTWF Huntington Thanks4Giving 4 Miler | TWF Huntington Thanks4Giving 4 Miler | 2025 |
| 18 | 24:21.40 | Danielle KatzTownwide Fund of Huntington Thanksgiving Day Run | Townwide Fund of Huntington Thanksgiving Day Run | 2021 |
| 19 | 24:24.95 | Annika SissonEJ Autism Jigsaw 4 Mile Run/Walk | EJ Autism Jigsaw 4 Mile Run/Walk | 2025 |
| 20 | 24:33 | Barbara GubbinsEarth Day 4 Mile Run | Earth Day 4 Mile Run | 2002 |
| 21 | 24:35.49 | Jacqueline TierneyIndependence Day 4 Mile Run/Walk | Independence Day 4 Mile Run/Walk | 2022 |
| 22 | 24:35.69 | Kerry GayeTownwide Fund of Huntington Thanksgiving Day 4 Mile | Townwide Fund of Huntington Thanksgiving Day 4 Mile | 2019 |
| 23 | 24:42.56 | Jacqueline KasteNavy SEAL LT Michael P. Murphy 4 Mile Run/Walk Around the Lake | Navy SEAL LT Michael P. Murphy 4 Mile Run/Walk Around the Lake | 2017 |
| 24 | 24:47.83 | Vivien LimIndependence Day 4 Mile Run/Walk | Independence Day 4 Mile Run/Walk | 2022 |
| 25 | 24:51.03 | Finnley WickardTWF Huntington Thanks4Giving 4 Miler | TWF Huntington Thanks4Giving 4 Miler | 2025 |
| 26 | 24:51.35 | Isabella GarraTWF Huntington Thanks4Giving 4 Miler | TWF Huntington Thanks4Giving 4 Miler | 2025 |
| 27 | 24:53.96 | Sarah BiggersTWF Huntington Thanks4Giving 4 Miler | TWF Huntington Thanks4Giving 4 Miler | 2025 |
| 28 | 24:58.79 | Nicole FreemanNavy SEAL LT Michael P Murphy 4 Mile Run | Walk Around the Lake | Navy SEAL LT Michael P Murphy 4 Mile Run | Walk Around the Lake | 2018 |
| 29 | 24:58.89 | Amanda AsheLong Beach 4 Mile Snowflake Race | Long Beach 4 Mile Snowflake Race | 2023 |
| 30 | 25:03.28 | Cristin Delaney-GuilleTownwide Fund of Huntington Thanksgiving Day Run | Townwide Fund of Huntington Thanksgiving Day Run | 2021 |
| 31 | 25:05.48 | Alison CaruanaIndependence Day 4 Mile Run/Walk | Independence Day 4 Mile Run/Walk | 2022 |
| 32 | 25:07.72 | Laura GannTownwide Fund of Huntington Thanksgiving Day 4 Mile | Townwide Fund of Huntington Thanksgiving Day 4 Mile | 2018 |
| 33 | 25:10 | Marline Mignano7th ANNUAL ROTARY 4 MILE RUN | 7th ANNUAL ROTARY 4 MILE RUN | 2004 |
| 34 | 25:10.28 | Michele MurrayJigsaw 4 Mile Run | Jigsaw 4 Mile Run | 2019 |
| 35 | 25:10.73 | Camryn SzokoliTWF Huntington Thanks4Giving 4 Miler | TWF Huntington Thanks4Giving 4 Miler | 2025 |
| 36 | 25:12.34 | Maria MarasciaNavy SEAL LT Michael P Murphy 4 Mile Run/Walk Around the Lake | Navy SEAL LT Michael P Murphy 4 Mile Run/Walk Around the Lake | 2019 |
| 37 | 25:13.93 | Kailey UreskTWF Huntington Thanks4Giving 4 Miler | TWF Huntington Thanks4Giving 4 Miler | 2025 |
| 38 | 25:14 | Tracey ContantA.Y.S. 4 MILE RUN/WALK for CYSTIC FIBROSIS | A.Y.S. 4 MILE RUN/WALK for CYSTIC FIBROSIS | 2004 |
| 39 | 25:18.32 | Lauren HoffmanTWF Huntington Thanks4Giving 4 Miler | TWF Huntington Thanks4Giving 4 Miler | 2024 |
| 40 | 25:19 | Vikki McKane6th ANNUAL 4 MILE RUN/WALK for CYSTIC FIBROSIS | 6th ANNUAL 4 MILE RUN/WALK for CYSTIC FIBROSIS | 2003 |
| 41 | 25:22.00 | Caitlin KennedyTownwide Fund of Huntington Thanksgiving Day 4 Mile | Townwide Fund of Huntington Thanksgiving Day 4 Mile | 2019 |
| 42 | 25:26.63 | Sayla FivesTownwide Fund of Huntington Thanksgiving 4 Mile | Townwide Fund of Huntington Thanksgiving 4 Mile | 2023 |
| 43 | 25:34 | Uma BroderickA.Y.S. 4 MILE RUN/WALK for CYSTIC FIBROSIS | A.Y.S. 4 MILE RUN/WALK for CYSTIC FIBROSIS | 2004 |
| 44 | 25:34.71 | Maria WilliamsIndependence Day 4 Mile Run/Walk | Independence Day 4 Mile Run/Walk | 2023 |
| 45 | 25:35.54 | Una BroderickEJ Foundation Jigsaw 4 Mile Run | EJ Foundation Jigsaw 4 Mile Run | 2018 |
| 46 | 25:35.96 | Fiona KingTownwide Fund of Huntington Thanksgiving 4 Mile | Townwide Fund of Huntington Thanksgiving 4 Mile | 2022 |
| 47 | 25:40.93 | Kathy DavidsonThe Long Beach Snowflake 4 Mile Race | The Long Beach Snowflake 4 Mile Race | 2026 |
| 48 | 25:42.74 | Mia WickardTownwide Fund of Huntington Thanksgiving Day Run | Townwide Fund of Huntington Thanksgiving Day Run | 2021 |
| 49 | 25:45.75 | Dana CarusoIndependence Day 4 Mile Run/Walk | Independence Day 4 Mile Run/Walk | 2022 |
| 50 | 25:55 | Kathleen Callahan-FodorCpl Chris Scherer I Did the Grid 4 Mile Run | Cpl Chris Scherer I Did the Grid 4 Mile Run | 2010 |
| 51 | 25:56.85 | Alanna HollbornJigsaw 4 Mile Run | Jigsaw 4 Mile Run | 2019 |
| 52 | 25:58.66 | Kimberly LarsonNavy SEAL LT Michael P Murphy 4 Mile Run | Walk Around the Lake | Navy SEAL LT Michael P Murphy 4 Mile Run | Walk Around the Lake | 2018 |
| 53 | 25:59.3 | Nancy TantoneSnowflake 4 Mile | Snowflake 4 Mile | 2020 |
| 54 | 25:59.59 | Fiona McLoughlinTownwide Fund of Huntington Thanksgiving Day 4 Mile | Townwide Fund of Huntington Thanksgiving Day 4 Mile | 2018 |
| 55 | 26:00.11 | Isabella DipalermoNavy SEAL LT Michael P Murphy 4 Mile Run | Walk Around the Lake | Navy SEAL LT Michael P Murphy 4 Mile Run | Walk Around the Lake | 2018 |
| 56 | 26:00.50 | Margaret PowersTownwide Fund of Huntington Thanksgiving 4 Mile | Townwide Fund of Huntington Thanksgiving 4 Mile | 2022 |
| 57 | 26:01.43 | Fiona HaegelandTownwide Fund of Huntington Thanksgiving Day 4 Mile | Townwide Fund of Huntington Thanksgiving Day 4 Mile | 2019 |
| 58 | 26:03.39 | Olivia PessoJigsaw 4 Mile Run | Jigsaw 4 Mile Run | 2019 |
| 59 | 26:04.43 | Jessica BaisleyEJ Autism 4 Mile Run/Walk | EJ Autism 4 Mile Run/Walk | 2026 |
| 60 | 26:06.13 | Amy HoganThe Long Beach Snowflake 4 Mile Race | The Long Beach Snowflake 4 Mile Race | 2025 |
| 61 | 26:09.72 | Emily ChesterIndependence Day 4 Mile Run/Walk | Independence Day 4 Mile Run/Walk | 2023 |
| 62 | 26:10.60 | Shannon O'HehirTownwide Fund of Huntington Thanksgiving Day 4 Mile | Townwide Fund of Huntington Thanksgiving Day 4 Mile | 2018 |
| 63 | 26:10.8 | Martha DelgadoSnowflake 4 Mile | Snowflake 4 Mile | 2020 |
| 64 | 26:12.28 | Mary FarnerTownwide Fund of Huntington Thanksgiving Day 4 Mile | Townwide Fund of Huntington Thanksgiving Day 4 Mile | 2018 |
| 65 | 26:14.02 | Christina MacHadoTownwide Fund of Huntington Thanksgiving Day 4 Mile | Townwide Fund of Huntington Thanksgiving Day 4 Mile | 2018 |
| 66 | 26:17 | Jennifer SchretzmayerA.Y.S. 4 MILE RUN/WALK for CYSTIC FIBROSIS | A.Y.S. 4 MILE RUN/WALK for CYSTIC FIBROSIS | 2004 |
| 67 | 26:19.26 | Riley GriffithTWF Huntington Thanks4Giving 4 Miler | TWF Huntington Thanks4Giving 4 Miler | 2025 |
| 68 | 26:24 | Sandra KolarA.Y.S. 4 MILE RUN/WALK for CYSTIC FIBROSIS | A.Y.S. 4 MILE RUN/WALK for CYSTIC FIBROSIS | 2004 |
| 69 | 26:27.47 | Jennifer Di StefanoNavy SEAL LT Michael P Murphy 4 Mile Run | Walk Around the Lake | Navy SEAL LT Michael P Murphy 4 Mile Run | Walk Around the Lake | 2018 |
| 70 | 26:29.96 | Christina GrandelliTownwide Fund of Huntington Thanksgiving Day 4 Mile | Townwide Fund of Huntington Thanksgiving Day 4 Mile | 2019 |
| 71 | 26:30.5 | Noni DegirmenciSnowflake 4 Mile | Snowflake 4 Mile | 2020 |
| 72 | 26:32.70 | Brittany GuttieriThe Hartigan St. Patrick's Run 4 Mile | The Hartigan St. Patrick's Run 4 Mile | 2019 |
| 73 | 26:32.87 | Danielle MiloNavy SEAL LT Michael P. Murphy 4 Mile Run/Walk Around the Lake | Navy SEAL LT Michael P. Murphy 4 Mile Run/Walk Around the Lake | 2016 |
| 74 | 26:33.5 | Abigail AthanasopoulosSnowflake 4 Mile | Snowflake 4 Mile | 2020 |
| 75 | 26:35.71 | Alyssa KnottIndependence Day 4 Mile Run/Walk | Independence Day 4 Mile Run/Walk | 2023 |
| 76 | 26:37.26 | Diana CeylanIndependence Day 4 Mile Run/Walk | Independence Day 4 Mile Run/Walk | 2023 |
| 77 | 26:37.63 | Meghan RhodesTownwide Fund of Huntington Thanksgiving Day 4 Mile | Townwide Fund of Huntington Thanksgiving Day 4 Mile | 2019 |
| 78 | 26:39.97 | Samantha ZoderThe 11th Annual Jigsaw 4 mile Run/Walk | The 11th Annual Jigsaw 4 mile Run/Walk | 2017 |
| 79 | 26:41.37 | RJ GrilloTWF Huntington Thanks4Giving 4 Miler | TWF Huntington Thanks4Giving 4 Miler | 2024 |
| 80 | 26:43.06 | Maria MadsenTownwide Fund of Huntington Thanksgiving Day 4 Mile | Townwide Fund of Huntington Thanksgiving Day 4 Mile | 2018 |
| 81 | 26:44.07 | Indiana Ripoll CidTownwide Fund of Huntington St. Patrick's Day 4 Mile Run | Townwide Fund of Huntington St. Patrick's Day 4 Mile Run | 2017 |
| 82 | 26:45.14 | Lisa RudloffTWF Huntington Thanks4Giving 4 Miler | TWF Huntington Thanks4Giving 4 Miler | 2025 |
| 83 | 26:45.84 | Sabrina FreydellTWF Huntington Thanks4Giving 4 Miler | TWF Huntington Thanks4Giving 4 Miler | 2025 |
| 84 | 26:48.6 | Jenna DeangeloSnowflake 4 Mile | Snowflake 4 Mile | 2020 |
| 85 | 26:49.23 | Jade CoyleEJ Autism 4 Mile Run/Walk | EJ Autism 4 Mile Run/Walk | 2026 |
| 86 | 26:50.09 | Margarita WickardTWF Huntington Thanks4Giving 4 Miler | TWF Huntington Thanks4Giving 4 Miler | 2025 |
| 87 | 26:50.10 | Whitney Dawson KrugTWF Huntington Thanks4Giving 4 Miler | TWF Huntington Thanks4Giving 4 Miler | 2024 |
| 88 | 26:50.25 | Danielle CornellJigsaw 4 Mile Run | Jigsaw 4 Mile Run | 2019 |
| 89 | 26:51.20 | Kirby MosenthalNavy SEAL LT Michael P Murphy 4 Mile Run | Walk Around the Lake | Navy SEAL LT Michael P Murphy 4 Mile Run | Walk Around the Lake | 2018 |
| 90 | 26:51.69 | Christine BorgTownwide Fund of Huntington Thanksgiving Day Run | Townwide Fund of Huntington Thanksgiving Day Run | 2021 |
| 91 | 26:55.02 | Giovanna CaponiTWF Huntington Thanks4Giving 4 Miler | TWF Huntington Thanks4Giving 4 Miler | 2025 |
| 92 | 26:59.50 | Riley AdamsIndependence Day 4 Mile Run/Walk | Independence Day 4 Mile Run/Walk | 2023 |
| 93 | 26:59.72 | Jennifer DistefanoNavy SEAL LT Michael P Murphy 4 Mile Run/Walk Around the Lake | Navy SEAL LT Michael P Murphy 4 Mile Run/Walk Around the Lake | 2019 |
| 94 | 27:00.58 | Leiba RimlerIndependence Day 4 Mile Run/Walk | Independence Day 4 Mile Run/Walk | 2022 |
| 95 | 27:01.87 | Kayla TrieschTWF Huntington Thanks4Giving 4 Miler | TWF Huntington Thanks4Giving 4 Miler | 2025 |
| 96 | 27:02.44 | Clara HalstonTownwide Fund of Huntington Thanksgiving Day 4 Mile | Townwide Fund of Huntington Thanksgiving Day 4 Mile | 2018 |
| 97 | 27:03 | Jessica Hampson6th ANNUAL 4 MILE RUN/WALK for CYSTIC FIBROSIS | 6th ANNUAL 4 MILE RUN/WALK for CYSTIC FIBROSIS | 2003 |
| 98 | 27:03.49 | Christina KlaumTownwide Fund of Huntington Thanksgiving Day 4 Mile | Townwide Fund of Huntington Thanksgiving Day 4 Mile | 2019 |
| 99 | 27:03.85 | Cecilia WinthropLong Beach 4 Mile Snowflake Race | Long Beach 4 Mile Snowflake Race | 2023 |
| 100 | 27:07 | Mara HartCpl Chris Scherer I Did the Grid 4 Mile Run | Cpl Chris Scherer I Did the Grid 4 Mile Run | 2010 |
